Reference
Jayagopal V, Kilpatrick ES, Jennings PE, Hepburn DA and Atkin SL, 2003, J Clin Endocrinol Metab, 88(4), 1528-33 , The Biological Variation of Testosterone and Sex Hormone-Binding Globulin (SHBG) in Polycystic Ovarian Syndrome: Implications for SHBG as a Surrogate Marker of Insulin Resistance
Parameter | Score |
---|---|
1. Scale | A |
2. Study Population | A |
3. Samples | A |
4. Measurand | A |
5. Pre-Analytical | A |
6. Replicate Analysis | A |
7. Steady State | A |
8. Outlier Analysis | C |
9. Normality | A |
10. Variance Homogeneity | A |
11. ANOVA | B |
12. CI | C |
13. No of Results | C |
14. Concentrations | A |
15. Total Score | C8,12,13 |
Comment |
Parameter | Score |
---|---|
Matrix | Serum |
Measurand | Sexual-hormone-binding-globulin (SHBG) |
Unit | nmol / L |
Overall Analytical Principle Method | Chemiluminescence |
Number of Subjects | 11 |
Number of Subjects included in BV estimation | |
Ethinicity | Caucasian |
Age Mean / Median | 30.0 |
Age Min | 19.0 |
Age Max | 33.0 |
Age SD | |
Number of Males | |
Number of Females | 11 |
State of Well Being |
Healthy (excl pregnant)
|
Diseases | |
Study Duration Length | 40 |
Study Duration Units | Day |
Sampling Intervals, e.g. X sample(s) per Interval Unit | 2 |
Interval Units | Week |
Sampling Times | Start Time:
8
End Time: 9 |
Number of Samples | 10 |
Average Number of Samples Used for BV Estimation | 10.0 |
Average Number of Replicates | 2.0 |
Estimates of CVi | 4.3 |
Calculated Confidence Intervals of CVi | Lower: 3.76, Upper: 5.01 |
Estimates of CVg | 94.7 |
Calculated Confidence Intervals of CVg | Lower: 0.00, Upper: 160.80 |
Analytical CV | 1.0 |
Calculated Confidence Intervals of Analytical CV | Lower: 0.88, Upper: 1.15 |
Measurand Mean | 64.51 |
Measurand Min | 56.86 |
Measurand Max | 72.16 |
Measurand SD |