Sexual-hormone-binding-globulin (SHBG)

Included in meta analysis

Reference

Reference
Jayagopal V, Kilpatrick ES, Jennings PE, Hepburn DA and Atkin SL, 2003, J Clin Endocrinol Metab, 88(4), 1528-33 , The Biological Variation of Testosterone and Sex Hormone-Binding Globulin (SHBG) in Polycystic Ovarian Syndrome: Implications for SHBG as a Surrogate Marker of Insulin Resistance

Originally from this reference: J Clin Endocrinol Metab, Jayagopal V, Kilpatrick ES, Jennings PE, Hepburn DA and Atkin SL, 2003


ID: 0404

Scoring

Total Score

C8,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA B
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Sexual-hormone-binding-globulin (SHBG)
Unit nmol / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 11
Number of Subjects included in BV estimation
Ethinicity Caucasian
Age Mean / Median 30.0
Age Min 19.0
Age Max 33.0
Age SD
Number of Males
Number of Females 11
State of Well Being Healthy (excl pregnant)
Study Duration Length 40
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time: 8
End Time: 9
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.3
Calculated Confidence Intervals of CVi Lower: 3.76, Upper: 5.01
Estimates of CVg 94.7
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 160.80
Analytical CV 1.0
Calculated Confidence Intervals of Analytical CV Lower: 0.88, Upper: 1.15
Measurand Mean 64.51
Measurand Min 56.86
Measurand Max 72.16
Measurand SD

Coding

Parameter Score
Healthy Population true
Adult Population true
Weekly Samplings true
Reviewed true
Published true
Gender for Meta-Analysis Females
Snomed CT
NPU
LOINC
Comment
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