Thyroxine - total (T4)


Oladipo O, Nenninger DA, Parvin Ca and Dietzen DJ, 2010, Clin Chim Acta, 411, 1143-5 , Intraindividual variability of thyroid function tests in a pediatric population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C5,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Thyroxine - total (T4)
Unit mmol / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 66
Number of Subjects included in BV estimation 66
Ethinicity Caucasian
Age Mean / Median
Age Min 0.0
Age Max 18.0
Age SD
Number of Males 34
Number of Females 32
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 14.5
Calculated Confidence Intervals of CVi Lower: 13.05, Upper: 15.94
Estimates of CVg 23.6
Calculated Confidence Intervals of CVg Lower: 19.89, Upper: 28.77
Analytical CV 6.2
Calculated Confidence Intervals of Analytical CV Lower: 5.08, Upper: 7.96
Measurand Mean 133.0
Measurand Min
Measurand Max
Measurand SD