EFLM Biological Varation Database : BIVAC Minimum Data Set for Total thyroxine level EFLM Biological Variation

Total thyroxine level

Reference

Oladipo O, Nenninger DA, Parvin Ca and Dietzen DJ, 2010, Clin Chim Acta, 411, 1143-5 , Intraindividual variability of thyroid function tests in a pediatric population

Originally from this reference: Clin Chim Acta, Oladipo O, Nenninger DA, Parvin Ca and Dietzen DJ, 2010

ID: 0413

Scoring

Total Score

C_5,8,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	C
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_5,8,10,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Total thyroxine level
Unit	mmol / L
Overall Analytical Principle Method	Immunoassay; Not specified
Number of Subjects	66
Number of Subjects included in BV estimation	66
Ethinicity	Caucasian
Age Mean / Median
Age Min	0.0
Age Max	18.0
Age SD
Number of Males	34
Number of Females	32
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units	Week
Sampling Times	Start Time: End Time:
Number of Samples	6
Average Number of Samples Used for BV Estimation	6.0
Average Number of Replicates	1.0
Estimates of CVi	14.5
Calculated Confidence Intervals of CVi	Lower: 13.05, Upper: 15.94
Estimates of CVg	23.6
Calculated Confidence Intervals of CVg	Lower: 19.89, Upper: 28.77
Analytical CV	6.2
Calculated Confidence Intervals of Analytical CV	Lower: 5.08, Upper: 7.96
Measurand Mean	133.0
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	false
Adult Population	false
Weekly Samplings	false
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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