EFLM Biological Varation Database : BIVAC Minimum Data Set for Total thyroxine level EFLM Biological Variation

Total thyroxine level

Reference

Ricós C and Arbós MA, 1990, Ann Clin Biochem, 27, 353-8 , Quality goals for hormone testing

Originally from this reference: Ann Clin Biochem, Ricós C and Arbós MA, 1990

ID: 0137

Scoring

Total Score

C_4,8,10

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	C
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	A
13. No of Results	A
14. Concentrations	B
15. Total Score	C_4,8,10
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Total thyroxine level
Unit	_ / _
Overall Analytical Principle Method	Immunoassay; ELISA
Number of Subjects	15
Number of Subjects included in BV estimation	15
Ethinicity	Caucasian
Age Mean / Median
Age Min	25.0
Age Max	40.0
Age SD
Number of Males	6
Number of Females	9
State of Well Being	Healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Day
Sampling Times	Start Time: End Time:
Number of Samples	7
Average Number of Samples Used for BV Estimation	7.0
Average Number of Replicates	2.0
Estimates of CVi	3.5
Calculated Confidence Intervals of CVi	Lower: 2.54, Upper: 4.50
Estimates of CVg	10.8
Calculated Confidence Intervals of CVg	Lower: 7.89, Upper: 16.84
Analytical CV	4.2
Calculated Confidence Intervals of Analytical CV	Lower: 3.70, Upper: 4.86
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	false
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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