Included in meta analysis


Hammond J, Wentz P, Statland BE, Phillips JC and Winkel P, 1976, Clin Chim Acta, 73, 347-52 , Daily variation of lipids and hormones in sera of healthy subjects


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7,8,10

Item Details

Parameter Score
Matrix Serum
Measurand Cortisol
Unit ug / dL
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 14
Number of Subjects included in BV estimation 14
Ethinicity Caucasian
Age Mean / Median
Age Min 23.0
Age Max 40.0
Age SD
Number of Males 8
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Week
Sampling Times Start Time: 8
End Time: 8:30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 2.0
Estimates of CVi 26.6
Calculated Confidence Intervals of CVi Lower: 22.34, Upper: 32.40
Estimates of CVg 53.1
Calculated Confidence Intervals of CVg Lower: 38.05, Upper: 84.88
Analytical CV 12.4
Calculated Confidence Intervals of Analytical CV Lower: 10.78, Upper: 14.61
Measurand Mean 18.4
Measurand Min
Measurand Max
Measurand SD