Thyroxine - free (FT4)

Included in meta analysis


Ankrah-Tetteh T, Wijeratne S and Swaminathan R, 2008, Ann Clin Biochem, 45, 167-9 , Intraindividual variation in serum thyroid hormones, parathyroid hormone and insulin-like growth factor-1


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Thyroxine - free (FT4)
Unit pmol / L
Overall Analytical Principle Method Immunoassay; Competitive
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median 21.0
Age Min 19.0
Age Max 27.0
Age SD
Number of Males 4
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 12.30
End Time: 14.30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 4.8
Calculated Confidence Intervals of CVi Lower: 1.42, Upper: 6.23
Estimates of CVg 11.7
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 20.77
Analytical CV 2.4
Calculated Confidence Intervals of Analytical CV Lower: 1.55, Upper: 5.29
Measurand Mean 15.0
Measurand Min 11.1
Measurand Max 21.0
Measurand SD