Sartorius G, Spasevska S, Idan A et al, 2012, Clin Endocrinol, 77, 755-63 , Serum testosterone, dihydrotestosterone and estradiol concentrations in older men self-reporting very good health: the healthy man study


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Testosterone
Unit nmol / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 325
Number of Subjects included in BV estimation 325
Ethinicity Caucasian
Age Mean / Median 60.0
Age Min 40.0
Age Max 97.0
Age SD
Number of Males 325
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 3
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 11:00
Number of Samples 9
Average Number of Samples Used for BV Estimation 9.0
Average Number of Replicates 1.0
Estimates of CVi 11.8
Calculated Confidence Intervals of CVi Lower: 5.87, Upper: 15.64
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 2.0
Calculated Confidence Intervals of Analytical CV Lower: 1.85, Upper: 2.18
Measurand Mean 16.7
Measurand Min 2.9
Measurand Max 33.9
Measurand SD