Thyroxine - total (T4)

Included in meta analysis


Juan-Pereira L., Navarro M. A., Roca M., Fuentes-Arderiu X, 1991, Clin Chem, 37, 772-773 , Within-subject variation of thyroxin and triiodo thyronine concentration in serum


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10,11

Item Details

Parameter Score
Matrix Serum
Measurand Thyroxine - total (T4)
Unit nmol / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 20
Number of Subjects included in BV estimation 20
Ethinicity Caucasian
Age Mean / Median
Age Min 24.0
Age Max 70.0
Age SD
Number of Males 6
Number of Females 14
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 1.0
Estimates of CVi 7.4
Calculated Confidence Intervals of CVi Lower: 1.82, Upper: 9.28
Estimates of CVg 12.1
Calculated Confidence Intervals of CVg Lower: 9.05, Upper: 17.75
Analytical CV 7.6
Calculated Confidence Intervals of Analytical CV Lower: 5.93, Upper: 10.57
Measurand Mean 116.0
Measurand Min
Measurand Max
Measurand SD