Testosterone

Reference

Reference
Collier CP, Morales A, Clark A, Lam M, Wynne-Edwards K and Black A, 2010, J Urol, 183, 2294-9 , The significance of biological variation in the diagnosis of testosterone deficiency, and consideration of the relevance of total, free and bioavailable testosterone determinations

Scoring

Total Score

C3,8,10,11,12

Parameter Score
1. Scale A
2. Study Population A
3. Samples C
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA C
12. CI C
13. No of Results A
14. Concentrations A
15. Total Score C3,8,10,11,12
Comment

Item Details

Parameter Score
Matrix Unknown
Measurand Testosterone
Unit ng / dL
Overall Analytical Principle Method Immunoassay; Competitive
Number of Subjects 87
Number of Subjects included in BV estimation 87
Ethinicity Caucasian
Age Mean / Median
Age Min 50.0
Age Max 80.0
Age SD
Number of Males 87
Number of Females
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Month
Sampling Times Start Time: 7
End Time: 10
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 18.7
Calculated Confidence Intervals of CVi Lower: 15.84, Upper: 22.26
Estimates of CVg 33.6
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 40.39
Analytical CV 6.0
Calculated Confidence Intervals of Analytical CV Lower: 4.50, Upper: 8.99
Measurand Mean 11.9
Measurand Min 2.8
Measurand Max 31.1
Measurand SD

Coding