Thyroxine - total (T4)

Reference

Reference
Browning MC, Bennet WM, Kirkaldy AJ, Jung RT., 1988, Clin Chem, 34(4), 696-9 , Intra-individual variation of thyroxin, triiodothyronine, and thyrotropin in treated hypothyroid patients: implications for monitoring replacement therapy.

Scoring

Total Score

C8,12

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI C
13. No of Results A
14. Concentrations A
15. Total Score C8,12
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Thyroxine - total (T4)
Unit nmol / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 12
Number of Subjects included in BV estimation 12
Ethinicity Caucasian
Age Mean / Median
Age Min 32.0
Age Max 76.0
Age SD
Number of Males 1
Number of Females 11
State of Well Being
Non-healthy (excl pregnant)
Diseases
Study Duration Length 8
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 2.0
Estimates of CVi 5.1
Calculated Confidence Intervals of CVi Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV
Calculated Confidence Intervals of Analytical CV Lower: , Upper:
Measurand Mean 118.0
Measurand Min
Measurand Max
Measurand SD

Coding