Reference
Browning MC, Ford RP, Callaghan SJ, Fraser CG., 1986, Clin Chem. 32(6):962-6., 32(6), 962-6 , Intra- and interindividual biological variation of five analytes used in assessing thyroid function: implications for necessary standards of performance and the interpretation of results.
Originally from this reference: Clin Chem. 32(6):962-6., Browning MC, Ford RP, Callaghan SJ, Fraser CG., 1986
ID: 0017
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | B |
| 8. Outlier Analysis | C |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | C |
| 14. Concentrations | A |
| 15. Total Score | C8,10,13 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | TSH level |
| Unit | mUI / L |
| Overall Analytical Principle Method | Immunoassay; Time-resolved immunofluorometric assay (TR-IMFA) |
| Number of Subjects | 12 |
| Number of Subjects included in BV estimation | 12 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 22.0 |
| Age Max | 46.0 |
| Age SD | |
| Number of Males | 6 |
| Number of Females | 6 |
| State of Well Being | Healthy (excl pregnant) |
| Study Duration Length | 5 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 2 |
| Interval Units | Week |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 10.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 16.2 |
| Calculated Confidence Intervals of CVi | Lower: 14.06, Upper: 18.94 |
| Estimates of CVg | 31.7 |
| Calculated Confidence Intervals of CVg | Lower: 22.41, Upper: 52.80 |
| Analytical CV | 7.5 |
| Calculated Confidence Intervals of Analytical CV | Lower: 6.66, Upper: 8.59 |
| Measurand Mean | 1.34 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |
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European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu
European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu