Fraser CG, Williams P, 1983, Clin Chem, 29, 508-10 , Short-term biological variation of plasma analytes in renal disease


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10

Item Details

Parameter Score
Matrix Plasma
Measurand Glucose
Unit mmol / L
Overall Analytical Principle Method Electrochemistry
Number of Subjects 9
Number of Subjects included in BV estimation 9
Ethinicity Unknown
Age Mean / Median
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 48
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Day
Sampling Times Start Time:
End Time:
Number of Samples 14
Average Number of Samples Used for BV Estimation 9.0
Average Number of Replicates 2.0
Estimates of CVi 27.7
Calculated Confidence Intervals of CVi Lower: 23.81, Upper: 33.11
Estimates of CVg 8.1
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 20.42
Analytical CV 2.0
Calculated Confidence Intervals of Analytical CV Lower: 1.73, Upper: 2.36
Measurand Mean 91.8
Measurand Min
Measurand Max
Measurand SD 5.1