Carlsen S, Petersen PH, Skeie S, Skadberg O and Sandberg S, 2011, Clin Chem Lab Med, 49, 1501-7 , Within subject biological variation of glucose and HbA1c in healthy persons and in type 1 diabetes patients


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Item Details

Parameter Score
Matrix Plasma
Measurand Glucose
Unit mol / L
Overall Analytical Principle Method Spectrophotometry; Enzymatic
Number of Subjects 15
Number of Subjects included in BV estimation 13
Ethinicity Unknown
Age Mean / Median
Age Min 27.0
Age Max 59.0
Age SD
Number of Males 6
Number of Females 9
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 7:30
End Time: 9:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 8.3
Average Number of Replicates 2.0
Estimates of CVi 31.1
Calculated Confidence Intervals of CVi Lower: 27.22, Upper: 36.28
Estimates of CVg 16.3
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 29.57
Analytical CV 0.9
Calculated Confidence Intervals of Analytical CV Lower: 0.79, Upper: 1.04
Measurand Mean 154.8
Measurand Min 147.6
Measurand Max 162.0
Measurand SD