Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013, Clin Chem Lab Med, 51, 851-62 , Biological variation and reference change value of common clinical chemistry and haematologic laboratory analytes in the eldery population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8

Item Details

Parameter Score
Matrix Serum
Measurand Triglycerides
Unit mmol / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 64
Number of Subjects included in BV estimation 64
Ethinicity Caucasian
Age Mean / Median
Age Min 80.0
Age Max 99.0
Age SD
Number of Males
Number of Females 64
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 9:00
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 19.5
Calculated Confidence Intervals of CVi Lower: 17.68, Upper: 21.72
Estimates of CVg 30.4
Calculated Confidence Intervals of CVg Lower: 25.38, Upper: 37.36
Analytical CV 3.2
Calculated Confidence Intervals of Analytical CV Lower: 2.51, Upper: 4.42
Measurand Mean 1.18
Measurand Min
Measurand Max
Measurand SD