Cholesterol

Included in meta analysis

Reference

Reference
Alexander KS, Kazmierczak SC, Snyder CK, Oberdorf JA and Farrell DH, 2013, Clin Chem Lab Med , 51(9), 1875-82 , Prognostic utility of biochemical markers of cardiovascular risk: impact of biological variability

Scoring

Total Score

C8,12

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI C
13. No of Results A
14. Concentrations A
15. Total Score C8,12
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mg / dL
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 15
Number of Subjects included in BV estimation 15
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 54.0
Age SD
Number of Males 6
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 1
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 2.0
Estimates of CVi 7.6
Calculated Confidence Intervals of CVi Lower: 6.80, Upper: 8.59
Estimates of CVg 12.1
Calculated Confidence Intervals of CVg Lower: 8.80, Upper: 18.92
Analytical CV 3.0
Calculated Confidence Intervals of Analytical CV Lower: 2.72, Upper: 3.35
Measurand Mean 191.0
Measurand Min
Measurand Max
Measurand SD

Coding