Cholesterol

Included in meta analysis

Reference

Reference
Young DS, Harris EK and Cotlove E, 1971, Clin Chem, 17, 403-10 , Biological and analytic components of variation in long-term studies of serum constituents in normal subjects. IV. Results of a study designed to eliminate long-term analytic deviations.

Scoring

Total Score

C8,10

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA B
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mg / dL
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 9
Number of Subjects included in BV estimation 9
Ethinicity Caucasian
Age Mean / Median
Age Min 27.0
Age Max 34.0
Age SD
Number of Males 9
Number of Females
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:30
End Time: 09:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.19
Calculated Confidence Intervals of CVi Lower: 3.62, Upper: 4.96
Estimates of CVg 13.9
Calculated Confidence Intervals of CVg Lower: 9.51, Upper: 25.46
Analytical CV 0.75
Calculated Confidence Intervals of Analytical CV Lower: 0.65, Upper: 0.88
Measurand Mean 204.0
Measurand Min
Measurand Max
Measurand SD

Coding