EFLM Biological Varation Database : BIVAC Minimum Data Set for Cholesterol EFLM Biological Variation

Cholesterol

Reference

Winkel P, Statland BE and Bokelund H, 1974, Clin Chem, 20, 1520-7 , Factors Contributing to Intra-Individual Variation of serum constituents: 5. Short-Term day-to-day and within-hour variation of serum constituents in healthy subjects

Scoring

Total Score

C_8,10,12,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	B
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	C
13. No of Results	C
14. Concentrations	A
15. Total Score	C_8,10,12,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Cholesterol
Unit	mmol / L
Overall Analytical Principle Method	Enzymatic analysis - Not specified
Number of Subjects	11
Number of Subjects included in BV estimation	11
Ethinicity	Caucasian
Age Mean / Median
Age Min	21.0
Age Max	27.0
Age SD
Number of Males	11
Number of Females
State of Well Being	Healthy (excl pregnant)
Study Duration Length	2
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	3
Interval Units	Day
Sampling Times	Start Time: 11:00 End Time: 11:30
Number of Samples	5
Average Number of Samples Used for BV Estimation	5.0
Average Number of Replicates	2.0
Estimates of CVi	11.4
Calculated Confidence Intervals of CVi	Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV
Calculated Confidence Intervals of Analytical CV	Lower: , Upper:
Measurand Mean	4.45
Measurand Min
Measurand Max
Measurand SD

Coding

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