Included in meta analysis


Schectman G, Patsches M and Sasse EA, 1996, Clin Chem, 42, 732-7 , Variability in cholesterol measuraments: comparison of calculated and direct LDL cholesterol determinations


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,12,13

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mmol / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 35
Number of Subjects included in BV estimation 35
Ethinicity Caucasian
Age Mean / Median
Age Min 39.0
Age Max 65.0
Age SD
Number of Males 35
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 4.7
Calculated Confidence Intervals of CVi Lower: 3.80, Upper: 5.56
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 2.0
Calculated Confidence Intervals of Analytical CV Lower: 1.46, Upper: 3.15
Measurand Mean 6.0
Measurand Min
Measurand Max
Measurand SD