EFLM Biological Varation Database : BIVAC Minimum Data Set for Eosinophils EFLM Biological Variation

Eosinophils

Reference

Statland BE, Winkel P, Harris SC, Burdsall MJ, Saunders AM, 1977, Am J Clin Pathol, 69, 48-54 , Evaluation of biological sources of variation of leukocyte counts and other hematologic quantities using very precise automated analyzers

Originally from this reference: Am J Clin Pathol, Statland BE, Winkel P, Harris SC, Burdsall MJ, Saunders AM, 1977

ID: 0154

Scoring

Total Score

C_7,8,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	B
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_7,8,10,13
Comment

Item Details

Parameter	Score
Matrix	Whole Blood EDTA
Measurand	Eosinophils
Unit	Unknown / Unknown
Overall Analytical Principle Method	Flow cytometry - Laser
Number of Subjects	20
Number of Subjects included in BV estimation	20
Ethinicity	Unknown
Age Mean / Median	35.5
Age Min	24.0
Age Max	46.0
Age SD
Number of Males	10
Number of Females	10
State of Well Being	Healthy (excl pregnant)
Study Duration Length	3
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	3
Interval Units	Hour
Sampling Times	Start Time: 08.00 End Time:
Number of Samples	9
Average Number of Samples Used for BV Estimation	9.0
Average Number of Replicates	1.0
Estimates of CVi	19.9
Calculated Confidence Intervals of CVi	Lower: 17.43, Upper: 22.62
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	6.6
Calculated Confidence Intervals of Analytical CV	Lower: 4.99, Upper: 9.76
Measurand Mean	218.0
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment	Duplicate samples at the same time. Within day and between day variation.

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