EFLM Biological Varation Database : BIVAC Minimum Data Set for Mean corpuscular haemoglobin concentration (MCHC) EFLM Biological Variation

Mean corpuscular haemoglobin concentration (MCHC)

Reference

Coskun A, Carobene A, Kilercik M, Serteser M, Sandberg S, Aarsand AK, Fernandez-Calle P, Jonker N, Bartlett W, Díaz-Garzón J, Huet S, Kiziltas C, Dalgakiran I, Ugur E and Unsal I, 2018, Clin Chem Lab Med, , , Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects

Originally from this reference: Clin Chem Lab Med, Coskun A, Carobene A, Kilercik M, Serteser M, Sandberg S, Aarsand AK, Fernandez-Calle P, Jonker N, Bartlett W, Díaz-Garzón J, Huet S, Kiziltas C, Dalgakiran I, Ugur E and Unsal I, 2018

ID: 0346

Scoring

Total Score

A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	A
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	A
13. No of Results	A
14. Concentrations	A
15. Total Score	A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}
Comment

Item Details

Parameter	Score
Matrix	Whole Blood EDTA
Measurand	Mean corpuscular haemoglobin concentration (MCHC)
Unit	g / L
Overall Analytical Principle Method	Flow cytometry - Laser
Number of Subjects	17
Number of Subjects included in BV estimation	17
Ethinicity	Caucasian
Age Mean / Median	28.0
Age Min	19.0
Age Max	46.0
Age SD
Number of Males	0
Number of Females	17
State of Well Being	Healthy (excl pregnant)
Study Duration Length	10
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: 08.30 End Time: 10.30
Number of Samples	10
Average Number of Samples Used for BV Estimation	10.0
Average Number of Replicates	2.0
Estimates of CVi	0.97
Calculated Confidence Intervals of CVi	Lower: 0.83, Upper: 1.13
Estimates of CVg	1.59
Calculated Confidence Intervals of CVg	Lower: 1.17, Upper: 2.42
Analytical CV	0.79
Calculated Confidence Intervals of Analytical CV	Lower: 0.71, Upper: 0.88
Measurand Mean	327.1
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Females
Snomed CT
NPU
LOINC
Comment

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