Reference
Coskun A, Carobene A, Kilercik M, Serteser M, Sandberg S, Aarsand AK, Fernandez-Calle P, Jonker N, Bartlett W, Díaz-Garzón J, Huet S, Kiziltas C, Dalgakiran I, Ugur E and Unsal I, 2018, Clin Chem Lab Med, , , Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Whole Blood EDTA |
| Measurand | Reticulocyte haemoglobin equivalent (RET-He) |
| Unit | pg / pg |
| Overall Analytical Principle Method | Flow cytometry - Laser |
| Number of Subjects | 17 |
| Number of Subjects included in BV estimation | 17 |
| Ethinicity | Caucasian |
| Age Mean / Median | 28.0 |
| Age Min | 19.0 |
| Age Max | 46.0 |
| Age SD | |
| Number of Males | 0 |
| Number of Females | 17 |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 10 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
08.30
End Time: 10.30 |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 9.76 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 3.4 |
| Calculated Confidence Intervals of CVi | Lower: 3.04, Upper: 3.85 |
| Estimates of CVg | 6.59 |
| Calculated Confidence Intervals of CVg | Lower: 4.89, Upper: 9.96 |
| Analytical CV | 0.79 |
| Calculated Confidence Intervals of Analytical CV | Lower: 0.71, Upper: 0.89 |
| Measurand Mean | 32.4 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |