Reference
Buoro S, Carobene A, Seghezzi M, Manenti B, Pacioni A, Ceriotti F, Ottomano C and Lippi G, 2017, Clin Chim Acta, 473, 147-56 , Short and medium-term biological variation estimates of leukocytes extended to differential count and morphology-structural paràmetres (cell population data) in blood samples obtained from healthy people
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Whole blood |
| Measurand | Basophils |
| Unit | 10(9) / L |
| Overall Analytical Principle Method | Flow cytometry - Laser |
| Number of Subjects | 21 |
| Number of Subjects included in BV estimation | 21 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 18.0 |
| Age Max | 64.0 |
| Age SD | |
| Number of Males | 9 |
| Number of Females | 12 |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 5 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
08.00
End Time: 08.300 |
| Number of Samples | 5 |
| Average Number of Samples Used for BV Estimation | 5.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 12.8 |
| Calculated Confidence Intervals of CVi | Lower: 10.02, Upper: 16.05 |
| Estimates of CVg | 33.9 |
| Calculated Confidence Intervals of CVg | Lower: 25.69, Upper: 48.95 |
| Analytical CV | 12.2 |
| Calculated Confidence Intervals of Analytical CV | Lower: 10.75, Upper: 14.11 |
| Measurand Mean | 0.044 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |