Reference
Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos
Parameter | Score |
---|---|
1. Scale | A |
2. Study Population | A |
3. Samples | A |
4. Measurand | A |
5. Pre-Analytical | A |
6. Replicate Analysis | B |
7. Steady State | B |
8. Outlier Analysis | B |
9. Normality | B |
10. Variance Homogeneity | C |
11. ANOVA | A |
12. CI | A |
13. No of Results | B |
14. Concentrations | A |
15. Total Score | C10 |
Comment | 1) Data may not be used for estimation of RCV (9B). 2) Data is not necessarily representative for the total population (10C). |
Parameter | Score |
---|---|
Matrix | Serum |
Measurand | Cystatin C |
Unit | mg / L |
Overall Analytical Principle Method | Unknown |
Number of Subjects | 49 |
Number of Subjects included in BV estimation | 49 |
Ethinicity | Hispanic or Latino |
Age Mean / Median | 46.0 |
Age Min | 18.0 |
Age Max | 74.0 |
Age SD | |
Number of Males | 18 |
Number of Females | 31 |
State of Well Being |
Healthy (excl pregnant)
|
Diseases | |
Study Duration Length | 1 |
Study Duration Units | Month |
Sampling Intervals, e.g. X sample(s) per Interval Unit | 2 |
Interval Units | Month |
Sampling Times | Start Time:
End Time: |
Number of Samples | 2 |
Average Number of Samples Used for BV Estimation | 2.0 |
Average Number of Replicates | 2.0 |
Estimates of CVi | 5.2 |
Calculated Confidence Intervals of CVi | Lower: 4.18, Upper: 6.66 |
Estimates of CVg | 25.6 |
Calculated Confidence Intervals of CVg | Lower: 21.27, Upper: 32.04 |
Analytical CV | 2.9 |
Calculated Confidence Intervals of Analytical CV | Lower: 2.54, Upper: 3.37 |
Measurand Mean | 0.81 |
Measurand Min | |
Measurand Max | |
Measurand SD |