Reference
Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | B |
| 7. Steady State | B |
| 8. Outlier Analysis | B |
| 9. Normality | B |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | B |
| 14. Concentrations | A |
| 15. Total Score | C10 |
| Comment | 1) Data may not be used for estimation of RCV (9B). 2) Data is not necessarily representative for the total population (10C). |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Cystatin C |
| Unit | mg / L |
| Overall Analytical Principle Method | Unknown |
| Number of Subjects | 49 |
| Number of Subjects included in BV estimation | 49 |
| Ethinicity | Hispanic or Latino |
| Age Mean / Median | 46.0 |
| Age Min | 18.0 |
| Age Max | 74.0 |
| Age SD | |
| Number of Males | 18 |
| Number of Females | 31 |
| State of Well Being | Healthy (excl pregnant) |
| Study Duration Length | 1 |
| Study Duration Units | Month |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 2 |
| Interval Units | Month |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 2 |
| Average Number of Samples Used for BV Estimation | 2.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 5.2 |
| Calculated Confidence Intervals of CVi | Lower: 4.18, Upper: 6.66 |
| Estimates of CVg | 25.6 |
| Calculated Confidence Intervals of CVg | Lower: 21.27, Upper: 32.04 |
| Analytical CV | 2.9 |
| Calculated Confidence Intervals of Analytical CV | Lower: 2.54, Upper: 3.37 |
| Measurand Mean | 0.81 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |
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European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu
European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu