LDL Cholesterol

Included in meta analysis

Reference

Reference
Ortolá J, Castiñeiras MJ, Fuentes-Arderiu X., 1992, Clin Chem, 38, 56-9 , Biological variation data applied to the selection of serum lipid ratios used as risk markers of coronary heart disease.

Scoring

Total Score

C8,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
11. ANOVA B
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand LDL Cholesterol
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; Not specified
Number of Subjects 23
Number of Subjects included in BV estimation 23
Ethinicity Caucasian
Age Mean / Median
Age Min 20.0
Age Max 45.0
Age SD
Number of Males 23
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 14
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 12
Average Number of Samples Used for BV Estimation 11.5
Average Number of Replicates 1.0
Estimates of CVi 13.7
Calculated Confidence Intervals of CVi Lower: 12.55, Upper: 15.07
Estimates of CVg 24.5
Calculated Confidence Intervals of CVg Lower: 18.86, Upper: 34.60
Analytical CV 2.0
Calculated Confidence Intervals of Analytical CV Lower: 1.57, Upper: 2.76
Measurand Mean 3.66
Measurand Min
Measurand Max
Measurand SD

Coding