Cystatin C


Keevil BG, Kilpatrick ES, Nichols SP and Maylor PW, 1998, Clin Chem, 44, 1535-9 , Biological variation of cystatin C: implications for the assesment of glomerular filtration rate


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Cystatin C
Unit mg / L
Overall Analytical Principle Method Turbidimetry
Number of Subjects 12
Number of Subjects included in BV estimation
Ethinicity Caucasian
Age Mean / Median 40.0
Age Min 21.0
Age Max 55.0
Age SD
Number of Males 7
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Study Duration Length 18
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Month
Sampling Times Start Time: 14:00
End Time: 15:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 13.3
Calculated Confidence Intervals of CVi Lower: 11.29, Upper: 15.78
Estimates of CVg 8.1
Calculated Confidence Intervals of CVg Lower: 4.73, Upper: 14.69
Analytical CV 8.9
Calculated Confidence Intervals of Analytical CV Lower: 7.90, Upper: 10.19
Measurand Mean 0.65
Measurand Min
Measurand Max
Measurand SD