EFLM Biological Varation Database : BIVAC Minimum Data Set for Creatinine EFLM Biological Variation

Creatinine

Reference

Sambasivan AS, Lepage N and Filler G, 2005, Clin Chem, 51, 2215-6 , Cystatin C intrapatient variability in children with chronic kidney disease is less than serum creatinine

Originally from this reference: Clin Chem, Sambasivan AS, Lepage N and Filler G, 2005

ID: 0282

Scoring

Total Score

C_6,8,10,12,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	B
6. Replicate Analysis	C
7. Steady State	B
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	C
13. No of Results	C
14. Concentrations	A
15. Total Score	C_6,8,10,12,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Creatinine
Unit	micromol / L
Overall Analytical Principle Method	Enzymatic analysis - Not specified
Number of Subjects	38
Number of Subjects included in BV estimation	38
Ethinicity	Caucasian
Age Mean / Median	10.1
Age Min
Age Max
Age SD
Number of Males	19
Number of Females	19
State of Well Being	Healthy (excl pregnant)
Study Duration Length	18
Study Duration Units	Month
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units	Week
Sampling Times	Start Time: End Time:
Number of Samples	9
Average Number of Samples Used for BV Estimation
Average Number of Replicates	1.0
Estimates of CVi	13.0
Calculated Confidence Intervals of CVi	Lower: 12.03, Upper: 14.14
Estimates of CVg	36.0
Calculated Confidence Intervals of CVg	Lower: 29.31, Upper: 46.53
Analytical CV	1.8
Calculated Confidence Intervals of Analytical CV	Lower: 1.46, Upper: 2.36
Measurand Mean	52.4
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	false
Weekly Samplings	false
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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