Lactate dehydrogenase (LDH) activity


Trapé J, Montesinos J, Franquesa J, Sala M, Fígols C, Miguel A and Domenech M, 2012, Clin Chem Lab Med, 50, 927-9 , Determination of the biological variation of S100 β and lactate dehydrogenase in disease-free patients with malignant melanoma


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C5,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Lactate dehydrogenase (LDH) activity
Unit microkatal / L
Overall Analytical Principle Method Enzymatic analysis - IFCC method
Number of Subjects 32
Number of Subjects included in BV estimation 32
Ethinicity Unknown
Age Mean / Median 59.1
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 0
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation 4.2
Average Number of Replicates 1.0
Estimates of CVi 8.2
Calculated Confidence Intervals of CVi Lower: 6.48, Upper: 9.74
Estimates of CVg 12.8
Calculated Confidence Intervals of CVg Lower: 9.95, Upper: 17.34
Analytical CV 3.5
Calculated Confidence Intervals of Analytical CV Lower: 2.51, Upper: 5.78
Measurand Mean 6.3
Measurand Min
Measurand Max
Measurand SD