EFLM Biological Varation Database : BIVAC Minimum Data Set for Lactate dehydrogenase activity EFLM Biological Variation

Lactate dehydrogenase activity

Reference

Trapé J, Montesinos J, Franquesa J, Sala M, Fígols C, Miguel A and Domenech M, 2012, Clin Chem Lab Med, 50, 927-9 , Determination of the biological variation of S100 β and lactate dehydrogenase in disease-free patients with malignant melanoma

Scoring

Total Score

C_5,8,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	B
4. Measurand	A
5. Pre-Analytical	C
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_5,8,10,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Lactate dehydrogenase activity
Unit	microkatal / L
Overall Analytical Principle Method	Enzymatic analysis - IFCC method
Number of Subjects	32
Number of Subjects included in BV estimation	32
Ethinicity	Unknown
Age Mean / Median	59.1
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length
Study Duration Units	Month
Sampling Intervals, e.g. X sample(s) per Interval Unit	0
Interval Units	Month
Sampling Times	Start Time: End Time:
Number of Samples	10
Average Number of Samples Used for BV Estimation	4.2
Average Number of Replicates	1.0
Estimates of CVi	8.2
Calculated Confidence Intervals of CVi	Lower: 6.48, Upper: 9.74
Estimates of CVg	12.8
Calculated Confidence Intervals of CVg	Lower: 9.95, Upper: 17.34
Analytical CV	3.5
Calculated Confidence Intervals of Analytical CV	Lower: 2.51, Upper: 5.78
Measurand Mean	6.3
Measurand Min
Measurand Max
Measurand SD

Coding

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