Loh TP, Ranieri e and Metz MP, 2014, Am J Clin Pathol, 142, 657-63 , Derivation of pediatric within-individual biological variation by indirect sampling method


Total Score


Parameter Score
1. Scale A
2. Study Population B
3. Samples A
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis A
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results B
14. Concentrations B
15. Total Score C5,7,10,12
Comment 2 samples per subject; time of sample collection not given

Item Details

Parameter Score
Matrix Serum
Measurand Potassium
Unit Unknown / Unknown
Overall Analytical Principle Method Unknown
Number of Subjects 9356
Number of Subjects included in BV estimation 9356
Ethinicity Unknown
Age Mean / Median
Age Min 0.0
Age Max 19.0
Age SD
Number of Males
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation
Average Number of Replicates 1.0
Estimates of CVi 5.7
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 14.30
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 0.5
Calculated Confidence Intervals of Analytical CV Lower: 0.56, Upper: 0.56
Measurand Mean
Measurand Min
Measurand Max
Measurand SD