EFLM Biological Varation Database : BIVAC Minimum Data Set for Apolipoprotein B EFLM Biological Variation

Apolipoprotein B

Reference

Kafonek SD, Derby CA and Bachorik PS, 1992, Clin Chem, 38, 864-72 , Biological variability of lipoproteins and apolipoproteins in patients referred to a lipid clinic

Originally from this reference: Clin Chem, Kafonek SD, Derby CA and Bachorik PS, 1992

ID: 0093

Scoring

Total Score

C_8,10,11,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	A
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	C
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_8,10,11,13
Comment

Item Details

Parameter	Score
Matrix	Plasma
Measurand	Apolipoprotein B
Unit	g / L
Overall Analytical Principle Method	Immunoassay; Other
Number of Subjects	143
Number of Subjects included in BV estimation	143
Ethinicity	Unknown
Age Mean / Median	28.0
Age Min
Age Max
Age SD
Number of Males	79
Number of Females	64
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	2
Study Duration Units	Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units	Week
Sampling Times	Start Time: End Time:
Number of Samples	3
Average Number of Samples Used for BV Estimation	3.0
Average Number of Replicates	1.0
Estimates of CVi	6.4
Calculated Confidence Intervals of CVi	Lower: 5.75, Upper: 7.08
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	2.7
Calculated Confidence Intervals of Analytical CV	Lower: 2.23, Upper: 3.43
Measurand Mean	1.71
Measurand Min
Measurand Max
Measurand SD	0.46

Coding

Parameter	Score
Healthy Population	false
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment	LIPID DISORDER

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