LDL Cholesterol


Kafonek SD, Derby CA and Bachorik PS, 1992, Clin Chem, 38, 864-72 , Biological variability of lipoproteins and apolipoproteins in patients referred to a lipid clinic


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,11,13

Item Details

Parameter Score
Matrix Plasma
Measurand LDL Cholesterol
Unit mmol / L
Overall Analytical Principle Method Calculated
Number of Subjects 128
Number of Subjects included in BV estimation 128
Ethinicity Unknown
Age Mean / Median 28.0
Age Min
Age Max
Age SD
Number of Males 69
Number of Females 59
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 3
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 1.0
Estimates of CVi 7.8
Calculated Confidence Intervals of CVi Lower: 6.70, Upper: 8.79
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 4.3
Calculated Confidence Intervals of Analytical CV Lower: 3.51, Upper: 5.54
Measurand Mean 4.12
Measurand Min
Measurand Max
Measurand SD 1.28