Davie SJ, Whiting KL, Gould BJ., 1993, Ann Clin Biochem, 30, 260-64 , Biological variation in glycated proteins


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,13

Item Details

Parameter Score
Matrix Serum
Measurand Glucose
Unit mmol / L
Overall Analytical Principle Method Electrochemistry
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median
Age Min 18.0
Age Max 38.0
Age SD
Number of Males 4
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Day
Sampling Times Start Time: 9:00
End Time: 17:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 12.1
Calculated Confidence Intervals of CVi Lower: 10.51, Upper: 14.23
Estimates of CVg 3.2
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 7.92
Analytical CV 3.0
Calculated Confidence Intervals of Analytical CV Lower: 2.64, Upper: 3.48
Measurand Mean 86.4
Measurand Min
Measurand Max
Measurand SD