Qi Z, Chen Y, Zhang L, Ma X, Wang F, Cheng Q, Du J, Hao Y, Chi S, Cui W, 2016, Clin Chim Acta, 452, 87-91 , Biological variations of thirteen plasma biochemical indicators


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Plasma
Measurand Amylase
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - Non-IFCC method
Number of Subjects 40
Number of Subjects included in BV estimation 21
Ethinicity Asian
Age Mean / Median 46.0
Age Min 21.0
Age Max 68.0
Age SD
Number of Males 21
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 08:00
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 4.15
Calculated Confidence Intervals of CVi Lower: 3.53, Upper: 4.97
Estimates of CVg 26.8
Calculated Confidence Intervals of CVg Lower: 20.58, Upper: 38.35
Analytical CV 2.05
Calculated Confidence Intervals of Analytical CV Lower: 1.81, Upper: 2.37
Measurand Mean
Measurand Min 43.0
Measurand Max 112.0
Measurand SD