Cholesterol

Included in meta analysis

Reference

Reference
Harris EK, Kanofsky P, Shakarji G and Cotlove E, 1970, Clin Chem, 16, 1022-7 , Biological and analytic components of variation in long-term studies of serum constituents in normal subjects

Scoring

Total Score

C8,10,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mg / dL
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 14
Number of Subjects included in BV estimation 14
Ethinicity Caucasian
Age Mean / Median 30.0
Age Min
Age Max
Age SD
Number of Males
Number of Females 14
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 11
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08.30
End Time: 9.00
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 2.0
Estimates of CVi 6.4
Calculated Confidence Intervals of CVi Lower: 5.61, Upper: 7.35
Estimates of CVg 18.3
Calculated Confidence Intervals of CVg Lower: 13.33, Upper: 28.96
Analytical CV 3.9
Calculated Confidence Intervals of Analytical CV Lower: 3.52, Upper: 4.37
Measurand Mean 225.0
Measurand Min
Measurand Max
Measurand SD

Coding