Included in meta analysis


Gowans EMS, Fraser CG, 1988, Ann Clin Biochem, 25, 259-63 , Biological variation of serum and urine creatinine and creatinine clearance: ramifications for interpretation of results and patient care


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C10,13

Item Details

Parameter Score
Matrix Serum
Measurand Creatinine
Unit micromol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 15
Number of Subjects included in BV estimation 15
Ethinicity Unknown
Age Mean / Median
Age Min 20.0
Age Max 53.0
Age SD
Number of Males 8
Number of Females 7
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 09:00
End Time: 10:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.1
Calculated Confidence Intervals of CVi Lower: 3.46, Upper: 4.84
Estimates of CVg 14.1
Calculated Confidence Intervals of CVg Lower: 10.37, Upper: 21.89
Analytical CV 3.4
Calculated Confidence Intervals of Analytical CV Lower: 3.05, Upper: 3.83
Measurand Mean 78.0
Measurand Min
Measurand Max
Measurand SD