Fraser CG and Hearne CR, 1982, Ann Clin Biochem, 19, 431-4 , Components of variance of some plasma constituents in patiens with myocardial infarction


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10

Item Details

Parameter Score
Matrix Plasma
Measurand Sodium
Unit mmol / L
Overall Analytical Principle Method Ion-selective electrode
Number of Subjects 20
Number of Subjects included in BV estimation 20
Ethinicity Unknown
Age Mean / Median
Age Min 21.0
Age Max 65.0
Age SD
Number of Males
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 96
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 31
Average Number of Samples Used for BV Estimation 31.0
Average Number of Replicates 2.0
Estimates of CVi 1.5
Calculated Confidence Intervals of CVi Lower: 1.24, Upper: 1.74
Estimates of CVg 6.6
Calculated Confidence Intervals of CVg Lower: 5.04, Upper: 9.54
Analytical CV 2.6
Calculated Confidence Intervals of Analytical CV Lower: 2.46, Upper: 2.75
Measurand Mean 142.0
Measurand Min
Measurand Max
Measurand SD