Biosca C, Ricós C, Jiménez CV, Lauzurica R and Galimany R, 1997, Clin Chem, 43, 2206-8 , Model for establishing biological variation in non-healthy situations: renal posttranplantation data


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations B
15. Total Score C10

Item Details

Parameter Score
Matrix Serum
Measurand Sodium
Unit mmol / L
Overall Analytical Principle Method Unknown
Number of Subjects 19
Number of Subjects included in BV estimation 19
Ethinicity Caucasian
Age Mean / Median
Age Min 19.0
Age Max 64.0
Age SD
Number of Males 12
Number of Females 7
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 48
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 16
Interval Units Year
Sampling Times Start Time: unknown
End Time: unknown
Number of Samples 33
Average Number of Samples Used for BV Estimation 33.0
Average Number of Replicates 1.0
Estimates of CVi 1.1
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 1.44
Estimates of CVg 1.1
Calculated Confidence Intervals of CVg Lower: 0.81, Upper: 1.65
Analytical CV 1.7
Calculated Confidence Intervals of Analytical CV Lower: 1.45, Upper: 2.06
Measurand Mean
Measurand Min
Measurand Max
Measurand SD