Included in meta analysis


Ford RP, 1989, Ann Clin Biochem, 26, 281-5 , Essential data derived from biological variation for establishment and use of lipid analyses


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 12
Number of Subjects included in BV estimation
Ethinicity Caucasian
Age Mean / Median
Age Min 23.0
Age Max 48.0
Age SD
Number of Males 6
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.9
Calculated Confidence Intervals of CVi Lower: 4.24, Upper: 5.74
Estimates of CVg 17.3
Calculated Confidence Intervals of CVg Lower: 12.35, Upper: 28.64
Analytical CV 2.4
Calculated Confidence Intervals of Analytical CV Lower: 2.13, Upper: 2.75
Measurand Mean 6.07
Measurand Min
Measurand Max
Measurand SD