Demacker PNM, Schade RWB, Jansen RTP and Van't Laar A, 1982, Atherosclerosis, 45, 259-66 , Intra-individual variation of serum cholesterol, triglycerides and high density lipoprotein cholesterol in normal humans


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Triglycerides
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 4
Number of Subjects included in BV estimation 4
Ethinicity Unknown
Age Mean / Median 32.0
Age Min 21.0
Age Max 61.0
Age SD
Number of Males
Number of Females 4
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 4
Interval Units Day
Sampling Times Start Time: 9.00
End Time: 20.00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 23.8
Calculated Confidence Intervals of CVi Lower: 16.94, Upper: 39.49
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 4.3
Calculated Confidence Intervals of Analytical CV Lower: 3.20, Upper: 6.54
Measurand Mean
Measurand Min
Measurand Max
Measurand SD