EFLM Biological Varation Database : BIVAC Minimum Data Set for S100B EFLM Biological Variation

S100B

Reference

Trapé J, Montesinos J, Franquesa J, Sala M, Fígols C, Miguel A and Domenech M, 2012, Clin Chem Lab Med, 50, 927-9 , Determination of the biological variation of S100 β and lactate dehydrogenase in disease-free patients with malignant melanoma

Originally from this reference: Clin Chem Lab Med, Trapé J, Montesinos J, Franquesa J, Sala M, Fígols C, Miguel A and Domenech M, 2012

ID: 0274

Scoring

Total Score

C_8,10,12,13

Parameter	Score
1. Scale	A
2. Study Population	B
3. Samples	B
4. Measurand	A
5. Pre-Analytical	B
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	C
13. No of Results	C
14. Concentrations	A
15. Total Score	C_8,10,12,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	S100B
Unit	ug / L
Overall Analytical Principle Method	Immunoassay; Not specified
Number of Subjects	32
Number of Subjects included in BV estimation	32
Ethinicity	Caucasian
Age Mean / Median	59.1
Age Min
Age Max
Age SD	14.8
Number of Males
Number of Females
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Year
Sampling Intervals, e.g. X sample(s) per Interval Unit	4
Interval Units	Year
Sampling Times	Start Time: End Time:
Number of Samples
Average Number of Samples Used for BV Estimation	4.2
Average Number of Replicates
Estimates of CVi	14.2
Calculated Confidence Intervals of CVi	Lower: 12.29, Upper: 16.58
Estimates of CVg	66.3
Calculated Confidence Intervals of CVg	Lower: 53.15, Upper: 87.91
Analytical CV	3.5
Calculated Confidence Intervals of Analytical CV	Lower: 2.51, Upper: 5.78
Measurand Mean	0.0557
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	false
Adult Population	true
Weekly Samplings	false
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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