Prostate specific antigen (PSA)

Included in meta analysis

Reference

Reference
Carobene A, Guerra E, Locatelli M, Cucchiara V, Briganti A, Aarsand AK et al, 2018, Clin Chim Acta, 486, 185-91 , Biological variation estimates for prostate specific antigen from the European Biological Variation Study; consequences for diagnosis and monitoring of prostate cancer

Originally from this reference: Clin Chim Acta, Carobene A, Guerra E, Locatelli M, Cucchiara V, Briganti A, Aarsand AK et al, 2018


ID: 0348

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment EuUBIVAS

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ug / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 37
Number of Subjects included in BV estimation 35
Ethinicity Caucasian
Age Mean / Median 35.0
Age Min 22.0
Age Max 59.0
Age SD
Number of Males 37
Number of Females 0
State of Well Being Healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 8.8
Average Number of Replicates 1.89
Estimates of CVi 6.8
Calculated Confidence Intervals of CVi Lower: 6.20, Upper: 7.50
Estimates of CVg 42.0
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 54.82
Analytical CV 3.3
Calculated Confidence Intervals of Analytical CV Lower: 3.03, Upper: 3.62
Measurand Mean 0.85
Measurand Min 0.82
Measurand Max 0.89
Measurand SD 0.028

Coding

Parameter Score
Healthy Population true
Adult Population true
Weekly Samplings true
Reviewed true
Published true
Gender for Meta-Analysis Males
Snomed CT
NPU
LOINC
Comment EuBIVAS study
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