Included in meta analysis


Jensen E, Petersen PH, Blaabjerg O and Hegedüs L, 2007, Clin Chem Lab Med, 45, 1058-64 , Biological variation of thyroid autoantibodies and thyroglobulin


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8

Item Details

Parameter Score
Matrix Serum
Measurand Thyroglobulin
Unit ug / L
Overall Analytical Principle Method Fluoroimmunometry
Number of Subjects 24
Number of Subjects included in BV estimation 21
Ethinicity Caucasian
Age Mean / Median 35.5
Age Min 23.0
Age Max 46.0
Age SD
Number of Males
Number of Females 24
State of Well Being
Healthy (excl pregnant)
Study Duration Length 36
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time: 07:30
End Time: 11:00
Number of Samples 9
Average Number of Samples Used for BV Estimation 9.0
Average Number of Replicates 2.0
Estimates of CVi 16.2
Calculated Confidence Intervals of CVi Lower: 14.61, Upper: 18.17
Estimates of CVg 128.0
Calculated Confidence Intervals of CVg Lower: 98.41, Upper: 183.00
Analytical CV 2.9
Calculated Confidence Intervals of Analytical CV Lower: 2.63, Upper: 3.23
Measurand Mean
Measurand Min 0.0
Measurand Max 26.0
Measurand SD