EFLM Biological Varation Database : BIVAC Minimum Data Set for Thyroglobulin EFLM Biological Variation

Thyroglobulin

Reference

Jensen E, Petersen PH, Blaabjerg O and Hegedüs L, 2007, Clin Chem Lab Med, 45, 1058-64 , Biological variation of thyroid autoantibodies and thyroglobulin

Originally from this reference: Clin Chem Lab Med, Jensen E, Petersen PH, Blaabjerg O and Hegedüs L, 2007

ID: 0207

Scoring

Total Score

B_8,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	B
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	A
13. No of Results	B
14. Concentrations	A
15. Total Score	B_8,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Thyroglobulin
Unit	ug / L
Overall Analytical Principle Method	Fluoroimmunometry
Number of Subjects	24
Number of Subjects included in BV estimation	21
Ethinicity	Caucasian
Age Mean / Median	35.5
Age Min	23.0
Age Max	46.0
Age SD
Number of Males
Number of Females	24
State of Well Being	Healthy (excl pregnant)
Study Duration Length	36
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	2
Interval Units	Week
Sampling Times	Start Time: 07:30 End Time: 11:00
Number of Samples	9
Average Number of Samples Used for BV Estimation	9.0
Average Number of Replicates	2.0
Estimates of CVi	16.2
Calculated Confidence Intervals of CVi	Lower: 14.61, Upper: 18.17
Estimates of CVg	128.0
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper: 183.00
Analytical CV	2.9
Calculated Confidence Intervals of Analytical CV	Lower: 2.63, Upper: 3.23
Measurand Mean	5.1
Measurand Min	0.0
Measurand Max	16.3
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	true
Reviewed	false
Published	false
Gender for Meta-Analysis	Females
Snomed CT
NPU
LOINC
Comment	NB high CVg

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