Cancer antigen 19-9 (CA 19-9)

Reference

Reference
Plebani M, Giacomini A, Beghi L, De Paoli M, Roveroni G, Galleotti F, Corsini A, Fraser CG, 1996, Anticancer Res, 16, 2249-52 , Serum tumor markers in monitoring patients: interpretation of results using analytical and biological variation

Scoring

Total Score

C8,10,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA B
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,12,13
Comment C8,10,12

Item Details

Parameter Score
Matrix Serum
Measurand Cancer antigen 19-9 (CA 19-9)
Unit ku / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 17
Number of Subjects included in BV estimation 17
Ethinicity Unknown
Age Mean / Median 30.0
Age Min
Age Max
Age SD
Number of Males 9
Number of Females 8
State of Well Being
Non-healthy (excl pregnant)
Diseases
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 15.9
Calculated Confidence Intervals of CVi Lower: 13.75, Upper: 18.78
Estimates of CVg 159.0
Calculated Confidence Intervals of CVg Lower: 119.23, Upper: 238.48
Analytical CV 2.7
Calculated Confidence Intervals of Analytical CV Lower: 1.89, Upper: 4.74
Measurand Mean 17.1
Measurand Min
Measurand Max
Measurand SD

Coding