Cancer antigen 125 (CA-125)

Included in meta analysis


Braga F, Ferraro S, Mozzi R and Panteghini M, 2014, Clin Chem Lab Med, 52, 1625-31 , The importance of individual biology in the clinical use of serum biomarkers for ovarian cancer


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis B
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B7,8

Item Details

Parameter Score
Matrix Serum
Measurand Cancer antigen 125 (CA-125)
Unit ku / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 28
Number of Subjects included in BV estimation 28
Ethinicity Caucasian
Age Mean / Median
Age Min 25.0
Age Max 68.0
Age SD
Number of Males 0
Number of Females 28
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 09:00
End Time: 09:30
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 9.1
Calculated Confidence Intervals of CVi Lower: 7.88, Upper: 10.75
Estimates of CVg 10.6
Calculated Confidence Intervals of CVg Lower: 7.88, Upper: 14.93
Analytical CV 1.97
Calculated Confidence Intervals of Analytical CV Lower: 1.74, Upper: 2.27
Measurand Mean 12.3
Measurand Min 2.5
Measurand Max 35.8
Measurand SD