Carcinoembryonic antigen (CEA)

Reference

Reference
Trapé J, Perez de Olaguer J, Buxó J and López L, 2005, Clin Chem, 51, 219-22 , Biological variation of tumor markers and its aplication in the detection of disease progression in patients with non-samll cell lung cancer

Scoring

Total Score

C10,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI C
13. No of Results C
14. Concentrations B
15. Total Score C10,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Carcinoembryonic antigen (CEA)
Unit ug / L
Overall Analytical Principle Method Immunoassay; Competitive
Number of Subjects 30
Number of Subjects included in BV estimation 30
Ethinicity Caucasian
Age Mean / Median 61.1
Age Min
Age Max
Age SD
Number of Males 30
Number of Females
State of Well Being
Non-healthy (excl pregnant)
Diseases
Study Duration Length 6
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 4
Interval Units Year
Sampling Times Start Time:
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation
Average Number of Replicates 1.0
Estimates of CVi 9.9
Calculated Confidence Intervals of CVi Lower: 8.56, Upper: 11.66
Estimates of CVg 35.6
Calculated Confidence Intervals of CVg Lower: 28.28, Upper: 47.79
Analytical CV 2.1
Calculated Confidence Intervals of Analytical CV Lower: 1.51, Upper: 3.47
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding