Reference
Trapé J, Franquesa J, Sala M, Domenech M, Montesinos J, Catot S, Buxó J, Casado E, Fígols C, Harillo S, Galobart J and Bella M, 2010, Clin Chem Lab Med, 48, 1799-1801 , Determination of biological variation of -fetoprotein and choriogonadotropin ( chain) in disease-free patients with testicular cancer
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | B |
| 3. Samples | C |
| 4. Measurand | A |
| 5. Pre-Analytical | C |
| 6. Replicate Analysis | B |
| 7. Steady State | C |
| 8. Outlier Analysis | C |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | C |
| 12. CI | C |
| 13. No of Results | C |
| 14. Concentrations | A |
| 15. Total Score | C3,5,7,8,10,11,12,13 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Alphafetoprotein |
| Unit | ug / L |
| Overall Analytical Principle Method | Chemiluminescence |
| Number of Subjects | 28 |
| Number of Subjects included in BV estimation | 28 |
| Ethinicity | Unknown |
| Age Mean / Median | 33.3 |
| Age Min | 24.46 |
| Age Max | 42.14 |
| Age SD | 8.84 |
| Number of Males | 28 |
| Number of Females | |
| State of Well Being |
Non-healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | |
| Interval Units | Week |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | |
| Average Number of Samples Used for BV Estimation | |
| Average Number of Replicates | |
| Estimates of CVi | 12.4 |
| Calculated Confidence Intervals of CVi | Lower: 0.00, Upper: 450.74 |
| Estimates of CVg | 45.1 |
| Calculated Confidence Intervals of CVg | Lower: 0.00, Upper: 62.46 |
| Analytical CV | 7.1 |
| Calculated Confidence Intervals of Analytical CV | Lower: 3.70, Upper: 44.62 |
| Measurand Mean | 3.9 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |