Reference
Vestergaard EM, Hein HO, Meyer H, Grunnet N, Jorgensen J, Wolf H, Orntoft TF, 1999, Clin Chem, 45, 54-61 , Reference Values and Biological Variation for Tumor Marker CA 19-9 in Serum for Different Lewis and Secretor Genotypes and Evaluation of Secretor and Lewis Genotyping in a Caucasian Populatio
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | C |
| 6. Replicate Analysis | B |
| 7. Steady State | B |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | B |
| 12. CI | A |
| 13. No of Results | C |
| 14. Concentrations | B |
| 15. Total Score | C5,10,13 |
| Comment | C5,10,13 |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Cancer antigen 19-9 (CA 19-9) |
| Unit | ku / L |
| Overall Analytical Principle Method | Immunoassay; Not specified |
| Number of Subjects | 500 |
| Number of Subjects included in BV estimation | 13 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 21.0 |
| Age Max | 69.0 |
| Age SD | |
| Number of Males | 382 |
| Number of Females | 118 |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 3 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 3 |
| Average Number of Samples Used for BV Estimation | 3.0 |
| Average Number of Replicates | 3.0 |
| Estimates of CVi | 15.8 |
| Calculated Confidence Intervals of CVi | Lower: 11.90, Upper: 22.29 |
| Estimates of CVg | 102.2 |
| Calculated Confidence Intervals of CVg | Lower: 73.79, Upper: 165.10 |
| Analytical CV | 9.8 |
| Calculated Confidence Intervals of Analytical CV | Lower: 8.47, Upper: 11.62 |
| Measurand Mean | |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |