Carcinoembryonic antigen (CEA)

Reference

Reference
Sölétormos G, Schioler V, Nielsen D, Skovsgaard T, Domnerbowsky P, 1993, Clin Chem, 39, 2077-83 , Interpretation of results for tumor markers on the basis of analytical imprecision an biological variation

Scoring

Total Score

C8,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI C
13. No of Results C
14. Concentrations B
15. Total Score C8,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Carcinoembryonic antigen (CEA)
Unit ug / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 22
Number of Subjects included in BV estimation 22
Ethinicity Caucasian
Age Mean / Median 49.0
Age Min 34.0
Age Max 63.0
Age SD
Number of Males
Number of Females 22
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 28
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 14
Average Number of Samples Used for BV Estimation 14.0
Average Number of Replicates 1.0
Estimates of CVi 9.3
Calculated Confidence Intervals of CVi Lower: 4.27, Upper: 11.41
Estimates of CVg 86.8
Calculated Confidence Intervals of CVg Lower: 67.09, Upper: 122.90
Analytical CV 9.5
Calculated Confidence Intervals of Analytical CV Lower: 7.59, Upper: 12.70
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding