Neuron specific enolase

Included in meta analysis


Braga F, Ferraro S, Mozzi R, Dolci A, Panteghini M, 2013, Clinical Biochemistry, 46, 148-51 , Biological variation of neuroendocrine tumor markers chromogranin A and neuron-specific enolase.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B7

Item Details

Parameter Score
Matrix Serum
Measurand Neuron specific enolase
Unit ug / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 22
Number of Subjects included in BV estimation 22
Ethinicity Black or African American
Age Mean / Median
Age Min 23.0
Age Max 54.0
Age SD
Number of Males 10
Number of Females 12
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Month
Sampling Times Start Time: 9:00
End Time: 9:30
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 13.6
Calculated Confidence Intervals of CVi Lower: 11.57, Upper: 16.46
Estimates of CVg 11.5
Calculated Confidence Intervals of CVg Lower: 7.53, Upper: 17.67
Analytical CV 3.1
Calculated Confidence Intervals of Analytical CV Lower: 2.70, Upper: 3.64
Measurand Mean 10.8
Measurand Min
Measurand Max
Measurand SD