Tissue plasminogen activator (TPA)

Reference

Reference
Sölétormos G, Schioler V, Nielsen D, Skovsgaard T, Domnerbowsky P, 1993, Clin Chem, 39, 2077-83 , Interpretation of results for tumor markers on the basis of analytical imprecision an biological variation

Scoring

Total Score

C8,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI C
13. No of Results C
14. Concentrations B
15. Total Score C8,12,13
Comment C8,12,13

Item Details

Parameter Score
Matrix Serum
Measurand Tissue plasminogen activator (TPA)
Unit U / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 22
Number of Subjects included in BV estimation 21
Ethinicity Caucasian
Age Mean / Median 49.0
Age Min 34.0
Age Max 63.0
Age SD
Number of Males 0
Number of Females 22
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 3
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 5
Interval Units Week
Sampling Times Start Time: 07:30
End Time: 09:00
Number of Samples 14
Average Number of Samples Used for BV Estimation 14.0
Average Number of Replicates 1.0
Estimates of CVi 28.3
Calculated Confidence Intervals of CVi Lower: 25.12, Upper: 31.40
Estimates of CVg 133.0
Calculated Confidence Intervals of CVg Lower: 102.19, Upper: 190.25
Analytical CV 11.9
Calculated Confidence Intervals of Analytical CV Lower: 9.48, Upper: 16.00
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding