EFLM Biological Varation Database : BIVAC Minimum Data Set for Cancer antigen 15-3 (CA 15.3) EFLM Biological Variation

Cancer antigen 15-3 (CA 15.3)

Reference

Sölétormos G, Schioler V, Nielsen D, Skovsgaard T, Domnerbowsky P, 1993, Clin Chem, 39, 2077-83 , Interpretation of results for tumor markers on the basis of analytical imprecision an biological variation

Originally from this reference: Clin Chem, Sölétormos G, Schioler V, Nielsen D, Skovsgaard T, Domnerbowsky P, 1993

ID: 0151

Scoring

Total Score

C_8,12,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	B
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	A
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	C
13. No of Results	C
14. Concentrations	B
15. Total Score	C_8,12,13
Comment	C8,12,13

Item Details

Parameter	Score
Matrix	Serum
Measurand	Cancer antigen 15-3 (CA 15.3)
Unit	U / L
Overall Analytical Principle Method	Immunoassay; RIA
Number of Subjects	22
Number of Subjects included in BV estimation	21
Ethinicity	Caucasian
Age Mean / Median	49.0
Age Min	34.0
Age Max	63.0
Age SD
Number of Males	0
Number of Females	22
State of Well Being	Healthy (excl pregnant)
Study Duration Length	3
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	5
Interval Units	Week
Sampling Times	Start Time: 07:30 End Time: 09:00
Number of Samples	14
Average Number of Samples Used for BV Estimation	14.0
Average Number of Replicates	1.0
Estimates of CVi	6.2
Calculated Confidence Intervals of CVi	Lower: 0.00, Upper: 9.48
Estimates of CVg	62.9
Calculated Confidence Intervals of CVg	Lower: 48.35, Upper: 89.95
Analytical CV	11.2
Calculated Confidence Intervals of Analytical CV	Lower: 8.92, Upper: 15.06
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment

© 2018 - 2019 This website and its content is copyright of EFLM. All rights reserved. Any redistribution or reproduction of part or all of the contents in any form is prohibited other than the following: you may print or download to a local hard disk extracts for your personal and non-commercial use only you may copy the content to individual third parties for their personal use, but only if you acknowledge the website as the source of the material You may not, except with our express written permission, distribute or commercially exploit the content. Nor may you transmit it or store it in any other website or other form of electronic retrieval system.