| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | B |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | B7 |
| Comment | They should have checked the limit of detection. BV too high |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Cancer antigen 72-4 (CA 72-4) |
| Unit | ug / mL |
| Overall Analytical Principle Method | Immunoassay; Not specified |
| Number of Subjects | 20 |
| Number of Subjects included in BV estimation | 20 |
| Ethinicity | Caucasian |
| Age Mean / Median | 29.0 |
| Age Min | 22.0 |
| Age Max | 49.0 |
| Age SD | |
| Number of Males | 9 |
| Number of Females | 11 |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 5 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
7:20
End Time: 8:10 |
| Number of Samples | 5 |
| Average Number of Samples Used for BV Estimation | 5.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 50.3 |
| Calculated Confidence Intervals of CVi | Lower: 43.55, Upper: 59.54 |
| Estimates of CVg | 103.4 |
| Calculated Confidence Intervals of CVg | Lower: 77.71, Upper: 151.13 |
| Analytical CV | 4.0 |
| Calculated Confidence Intervals of Analytical CV | Lower: 3.51, Upper: 4.64 |
| Measurand Mean | 3.5 |
| Measurand Min | 0.6 |
| Measurand Max | 21.6 |
| Measurand SD |